In 2021, actors in the Indo-Pacific including ASEAN member countries and the Republic of Korea (ROK, hereafter referred to as Korea) have experienced changes and continuitities with the inauguration of the Biden administration. At the same time, continuing Sino-US rivalry and intensifying waves of COVID-19 infection globaly presented new challenges to the region's economy and threatened to erode multilateralism and rule-based order. In the long term, however, the region's seeing disintegration may also provide novel opportunities to forge new and innovative forms of cooperation and partnership in the Indo-Pacific. The book comprises contributions from nine distinguished experts who participated in the seminar, and H.E. Ambassador Ong Keng Yong and Ambassador Cho Byung-jae who have made great congtributions to ASEAN and ROK's progress honored this initiative by chairing Sessions 1 and 2. Chapter I of the book reviews strategies of ASEAN and ROK and their current bilateral partnership in cultural, economic, and political domains. Suggestions to strengthen the ties between ASEAN member countries and ROK are made based on the convergences in their respective Indo-Pacific strategies. Chapter II then turns to the broaded Indo-Pacific and focuses on ways to develop partnerships with other key stakeholders in the region such as the US, EU, and India. In this regrards, Chapter III emphasizes the ASEAN-ROK partnership central in these multilateral approaches to fostering cooperation and ensuring peace and prosperity in the Indo-Pacific.