In 2014, the Association of Southeast Asian Nations (ASEAN) and United Nations Children’s Fund (UNICEF) published the “Regional Report on Nutrition Security in ASEAN, Volume 1”, a compilation of the latest data on food and nutrition security and related factors, including a description of the policy and enabling environment for nutrition security in each of the ASEAN Member States. This, Volume 2 of the regional report, synthesizes the data from Volume 1, highlighting the causes and consequences of all forms of malnutrition in ASEAN Member States. The document also identifies key issues and challenges that need to be overcome for Member States to achieve the global World Health Assembly (WHA) nutrition targets in the context of the Sustainable Development Goals (SDGs). This evidence-based advocacy effort supports ASEAN’s commitments and actions to improve nutrition security as a national and regional development priority.