Responding to the call by the Fourth ASEAN Summit in Singapore in 1992, the ASEAN Task Force on AIDS (ATFOA) was established to implement regional activities on health and HIV and AIDS. ATFOA aims to curb and monitor the spread of HIV, and its work has been guided by global commitments on HIV and a series of work plans. HIV in the ASEAN Region is the second ASEAN Regional Report on HIV and AIDS and reports on the achievements of ASEAN Member States (AMS) in implementing the 4th ATFOA work plan for the period 2011 – 2015. In this period, AMS have been working towards the achievement of ambitious country-set targets under the umbrella of the UNAIDS 2011- 2015 strategy, Getting to Zero and guided by the goals enshrined in the 2011 ASEAN Declaration of Commitment: Getting to Zero New HIV Infections, Zero Discrimination, Zero AIDS-Related Deaths (Annex One)