This report highlights the most current patterns and trends of amphetamine-type stimulants and other drugs of use in East and Southeast Asia and provides overviews for the neighbouring regions of South Asia and the Pacific Island States and Territories. This report prepared under the Global Synthetics Monitoring: Analyses, Reporting and Trends (SMART) Programme. The Programme seeks to enhance the capacity of Member States and authorities in priority regions to generate, manage, analyse and report synthetic drug information and to apply this scientific evidence-based knowledge to design effective responses. A primary objective of this report is to help in improving the ability of states to respond to the growing human security and public health threats posed by the illicit manufacture, trafficking and use of synthetic drugs in the Asia and the Pacific region.