The scope of work of the ASEANTOM includes the following:

• Sharing best practices and experiences in regulating nuclear and radioactive materials and related activities, with regard to safety, security and safeguards;
• Capacity building by focusing on human resources development through training courses and technical collaboration;
• Assisting ASEAN Member States in the implementation of and adherence to their relevant commitments to the International Atomic Energy Agency (IAEA) standards and guidelines;
• Forging regional cooperation in areas such as nuclear emergency preparedness and response, environmental radiation monitoring, and nuclear security, including nuclear forensics and measures to combat illicit trafficking, unauthorised transfer of nuclear and radioactive materials; and
• Drawing on expertise and resources of ASEAN’s Dialogue Partners, other external parties, regional and international organisations as well as other relevant bodies and networks.