This issue of The ASEAN magazine attempts to paint a picture of the region’s current COVID-19 vaccination landscape. As with the rest of the world, our countries face devastating surges in COVID-19 cases caused by new and more infectious variants of the virus. Indonesia, the current chair of the ASEAN Health Ministers Meeting, Cambodia, and Thailand enlighten us on the progress of their national vaccination rollout strategies. The pace of vaccinations across the ASEAN Member States is increasing steadily, but we all face similar challenges of vaccine shortages, logistics, and hesitancy among our people.